​Toxicology narrative & MSDS comparison

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For part I of this assignment, use the NTP testing report or raw company
testing data

For part 2 of this assignment, use the Safety Data Sheets of hexane. Compare
the toxicology section of the MSDS to the information found on the ToxNet HSDB
documentation and compare the MSDS to the information found on ToxNext,
then answer the questions below.

1) You are a toxicologist for a company making a specific chemical and you are
tasked with writing a toxicology testing summary of this chemical. Please write a
comprehensive narrative of the toxicology associated with this chemical based
on the testing documentation provided on blackboard.
The company lawyer tells you: (i.e. what you’re grade for this section of the
assignment is based on

A) Your toxicology narrative for this summary must be less than 1500 words.

B) Your toxicology narrative must summarize how the toxicity testing information
provided supports the conclusions regarding:

what organ systems may be significantly affected
 Differentiate between chemically-related effects and those
that do not seem to be related to the chemical but rather
may have occurred due to testing artifact or the animal
models used (e.g. background animal cancer rates)
o what damage may occur, both reversible and irreversible
o Uncertainties in the information/testing available

2) In 1000 words or less, compare and contrast the toxicology section of the
MSDS’s for n-hexane provided with the information found on
ToxNet at:
https://toxnet.nlm.nih.gov/
Answer the following questions.

A) Does the MSDS accurately represent the toxicity of the chemical? Explain
your answer.
B) Does the MSDS provide a comprehensive picture of the toxicity? Why or why
not?
C) Do these sources of toxicity information convey the same message regarding
the hazards of the chemical? If not, how are they different?
D) Do you think the MSDS correctly conveys the toxicity of the chemical?
E) How might you change the MSDS to make it more comprehensive and
accurate?

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